MARINE FUNGI End-User Meeting

Research and Innovation 2014: Technology's Impact Into Cancer Research and Therapeutics

Date: March 11^th, 2014

Venue: Telford International Centre

Dedicated track:  Identifying New Bioactive Chemistry from Nature: Exploring the Potential of Marine Fungi.

The consortium set up a speakers program with representatives from industry and akademie and filled the conference room to the last place. Together with our booth the Marine Fungi consortium could increase their visibility to enable comercialisation of natural products and technological breakthrouths as well as process concepts for the sustainable production of substances discovered and proved successful up to in vivo test.

The conference hosted an exhibition were Marine Fungi was present with an innovation booth.

Presentations

Johannes Imhoff, GEOMAR - Marine Fungi: Strategy and General Overview    

Antje Labes, GEOMAR - Marine Fungi: Understanding the Biology of Marine Fungi for Produktion of Secondary Metabolites to Establish a Natural Produkt Library
   
Russell Cox,  Leibniz  University of Hannover - Understanding Fungal Biosynthetic Gene Clusters (available soon)
       
Phil Gribbon, European Screening Port: Marine Fungi - a  Phenotypic Assay Approach to Identifying Anti-­cancer Compounds
       
Eriko Takano, University of Manchester Biotechnology 2.0: Use of Synthetic Biology for Natural  Products (available soon)
       
Isabel Coma, GlaxoSmithKline: Mining Natural Products Screening Data for Target Class Chemical Motifs (available soon)
      
Esther Schmitt, Novartis Pharma AG: Innovation and Tradition in Industrial Natural Products Research

Lutz Müller-­Kuhrt,  Analyticon Discovery Novel Strategies for Natural Product Based Macrocyclic Libraries (available soon)  

Rebecca Goss, University of St. Andrews: Elucidating and Exploiting Biosynthesis (available soon)
  
Stephen Wrigley, Hypha Discovery Ltd: Marine Fungi - Charting the Chemistry of Hits from an Anticancer Screening Campaign   

Poster

A. Kramer/ H.C. Beck/ A. Kumar: Quantitative proteomics of the regulation patterns in scopularide A and B production by a marine Scopulariopsis brevicaulis strain LF580

A. Tamminen/ M. Wiebe:  Production of bioactive compound(s) with the marine fungus Calcarisporium sp Production of bioactive compound(s) with the marine fungus Calcarisporium sp

A. Tamminen/ M. Wiebe: Scopularide A production from the Marine Fungus Scopulariopsis brevicaulis

B. Ellinger et al.: A phenotypic screening approach to identify anti-cancer compounds derived from marine fungi

B. Kebede et al.: Establishing the Secondary Metabolite Profile of a Marine Fungus: Tolypocladium geodes MF458

J. Silber et al.: Bioactive metabolites of a marine Calcarisporium sp.

A Kumar & F Kempken: Genome sequencing, assembly and annotation of a marine fungal isolate of Scopulariopsis brevicaulis using three different next generation sequencing technologies

A Kumar & F Kempken: Next-generation genome and transcriptome based methods for the exploration of secondary metabolites from marine fungi for the treatment of cancer

K.S. Pedersen et al. : Phosphorylation dynamics in response to a novel anticancer compound from marine fungi

J. Landskron & K. Tjasken: Natural Products from Marine Fungi for the treatment of cancer

A. Stokka et al.: An EU-OPENSCREEN partner: The Chemical Biology Platform in Oslo

Date: Tuesday, December 3, 2013, 09:00 - 18:00

N. Taouatas, K. Pedersen (DTI) presented a poster

12 November 2013, Berlin , Germany

Venue: Embassy of the federal state of Schleswig-Holstein

Evening about research, exploitation and protection of the seas

Antje Labes presented the prospects of marine biotech for health

29.09-03.10.2013, Karlsruhe, Germany

Abhishek Kumar, CAU  talk: Next-generation genome and transcriptome based methods for the exploration of secondary metabolites from marine fungi for the treatment of cancer

23–25 September, 2013, Technical University of Braunschweig

Prof. Frank Kempken, CAU, chairs of the Plenary Session III • Regulatory RNAs & Fungal Genetics on Tuesday 24. September.

Linda Paun, CAU  poster: Random mutagenesis in filamentous fungi for higher yields of secondary metabolites

22 - 25 September 2013, DECHEMA-Haus, Frankfurt am Main

Bernhard Ellinger, ESP had a talk: A phenotypic screening toolbox permits the identification of novel compounds with anti-cancer properties derived from marine fungi

PACCT Seminar – Drug Discovery & Development Organisations, Lausanne, Switzerland

September 23rd 2013

talk: Dr. Phil Gribbon (CSO/COO) and Dr. Sheraz Gul (Vice President & Head of Biology) on "Small molecule drug discovery in the academic setting – case studies and future perspectives

"Innovative Uses of Baltic Marine Resources in the Light of the EU Blue Growth Initiative"

5–6 September 2013, Gdańsk, Poland

Antje Labes gave a talk: The KiWiZ – Centre for Marine Natural Product Research
 

Title: Application of next-generation genome and transcriptome based methods for the exploration of secondary metabolites from marine fungi for the treatment of cancer

German-Russian Forum Biotechnology, June 4. - 5., 2013, Rostock, Germany

Talk: A. Labes

Title: Early drug discovery from marine microbial resources

27-30.05.2013,  Antofagasta, Chile

Dristina Dorador, UA: Hongos marinos asociados a macroalgas: diversidad y bioactividad
"Marine Fungi associated to macroalgae: diversity and bioactivity"

Cristina Dorador (UA), Alexa Garín (UA) : Relaciones filogenéticas entre Emericellopsis y Acremonium, hongos marinos asociados a macroalgas
"Phylogenetic reationships between Emericellopsis and Acremonium, marine fungi associated to macroalgae"

resumee

24. May 2013

Kiel, Wissenschaftszentrum

Antje Labes gave an impulse talk on the future development of early drug development and how this can be implemented in a local strategy for blue biotech.

From 17. - 19. April 2013 the Consortium met in London at Westminster University and also visited Hypha Discovery´s Lab in Uxbridge.

Our Advisory Board Members Prof. Frank and Prof. Hylands joined us.
 

27th Fungal Genetics Conference, March 12 – 17
___________________________________________________________________________

Session: Prof. Frank Kempken

Title: Is fungal secondary metabolism regulated by competing insects?

Time: Saturday, March 16, 4.40 - 5 pm

Poster: Abhishek Kumar

Title: Genome sequencing, assembly and annotation of a marine fungal isolate of Scopulariopsis brevicaulis
        using three different next generation sequencing technologies

        Genome sequencing, assembly and annotation of a marine fungal isolate of Pestalotiopsis using next
        generation sequencing technologies.

        Genome sequencing, assembly and annotation of a marine fungal isolate of Calcariosporium using different
        next generation sequencing  technologies.

        Genome sequencing, assembly and annotation of three marine fungal isolates using different next generation
        DNA sequencing methods for pharmaceutically important secondary metabolites.
 

Poster: Linda Paun

Title: Higher yields of cyclodepsipeptides from Scopulariopsis brevicaulis by random mutagenesis

11. and 12. March in Brussels
________________________________________________________________________

present: Prof. J. Imhoff, Dr. A. Labes

Annual Conference of the Association for General and Applied Microbiology (VAAM)
in collaboration with the Royal Netherlands Society for Microbiology (KNVM)
10-13 March 2013 . Bremen, Germany

presentation: Antje Labes

Title: Genome based methods for the exploration of natural products from marine fungi for the treatment of cancer

Johanna Silber presented a poster

Title: Natural products from marine fungi for the treatment of cancer

The 18^th annual BIO-Europe^® international partnering conference was held in Hamburg, Germany November 12–14, 2012 at the CCH Congress Center Hamburg. Over 3,000 attendees from 48 countries had access to 3,000 projects available for partnering over three days. Delegates also scheduled upwards of 15,000 one-to-one partnering meetings utilizing partneringONE^®, EBD Group's leading conference networking solution.

ESP was present with a booth.

Eurofung Meeting, 15.10.2012, Berlin, Germany

Talk: Abishek Kumar (CAU)

Title: Genome and RNA sequencing, assembly and annotation of three marine fungal isolates using different next generation DNA sequencing methods for pharmaceutically important secondary metabolites

Basel, Switzerland, 24 – 27 September 2012

MipTec is the premier European conference and exhibition encompassing innovative approaches to high quality science and technology for efficient drug discovery.

www.miptec.ch

ELRIG – Drug Discovery 05.09.2012, Manchester, UK

Talk: Sheraz Gul (ESP)

Title: Use of phenotypic assays in academic drug discovery: challenges in identifying the funding, the compounds and the target

Vienna, Austria, 2-3 July 2012

poster presentation: Ann Jorunn Stokka

title: Norwegian Chemical Biology Platform - NOR-OPENSCREEN

For more information please visit:

http://ecbs2012.cemm.at

Frankfurt am Main, Germany, 18 - 22 June 2012

ACHEMA is the world forum of the process industry and the trend-setting technology summit for chemical engineering, environmental protection and biotechnology.
The 30^th ACHEMA was again the leading international meeting point for decision-makers and experts from all related industries.

GEOMAR and CAU have been present with a booth.

Talk: Antje Labes

Title: Genome based methods  for the exploration of natural products from marine fungi for the treatment of cancer

Talk: Abishek Kumar

Title: Genome sequencing, assembly and annotation of a marine fungal isolate of biotechnological interest (Scopulariopsis brevicaulis) using three different next generation sequencing technologies

www.achema.de

Boston, USA, June 18-21 June, 2012

Bio International Convention is the annual partnering and conference event of BIO that represents more than 1,100 biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations.

European Screeningport met with 30 companies and academic institutions at the partnering/networking event.

http://convention.bio.org

European Lab Automation, 30.05.2012, Hamburg

Poster: Jonas Weber

Title: Establishment of HTS MicroCarrier-based cell viability assays for NCI cancer cell lines using the BioLevitator™

Blue Biotech Cooperation Event: New strategies and future perspectives

Kiel, Germany 9–10 May 2012

Within the scope of the SUBMARINER project, the Center for Marine Natural Products (KiWiZ) at GEOMAR and Norgenta North German Life Science Agency GmbH hosted the Blue Biotechnology Cooperation Event "New Strategies and Future Perspectives".

Talk: Antje Labes

Title: Genome based methods for the exploration of natural products from marine fungi for the treatment of cancer

Poster: Annemarie Kramer

Title: Development of a miniaturised screening method for fungal mutants with enhanced production of specific natural compounds

Poster: Jonas Weber

Title: Hit Identification and Hit Profiling of Marine Fungi-derived Anti Cancer Agents Using a Cell-based Cytotoxicity Assay

Poster: Johanna Silber

Title: Marine fungi: a rich source for natural products

Poster: Abishek Kumar

Title: The draft genome of marine isolate of Scopulariopsis brevicaulis using three different next generation sequencing methods

http://www.submariner-project.eu

Genesis Conference, 01.12.2011, London

Talk: Liam Evans

Title: Natural Products: Last Resort or Smarter Choice for Drug Discovery

Prokagenomics 20.09.2011, Göttingen, Germany

Talk: Antje Labes

Title: Genome Based Methods for the Exploration of Natural Products from Marine Fungi for the Treatment of Cancer

2. Kongress Industrielle Zelltechnik, 02.09.2011,  Lübeck, Germany

Talk: Mira Grättinger

Title: Zellbasierte Technologien in  Drug Discovery & High-Throughput Screening  – Hope and Reality

XXXIII Congreso Chileno de Microbiología, Olmué, Chile. 29.11.2011

Poster: Cristina Dorador

Title: Aislamiento e identificación de hongos asociados a macroalgas desde las costas de Punta Piqueros y Bolsico, Antofagasta, Chile

Norwegian Technical-Natural Sciences Association

Biotechnology Seminar on Bioprospecting,12.05.2011, Oslo

Talk: Kjetl Tasken

Title: Biotechnology Infrastructure for marine bioprospecting