Natural Products from Marine Fungi for the treatment of cancer
The MarineFungi consortium demonstrated the sustainable exploitation of marine natural resources providing appropriate culture conditions. New anti cancer compounds are now characterised to the stage of in vivo proof of concept ready to enter further drug development.
We developed the technological basis for a sustainable use of marine microbial products along the added-value chain from the marine habitat to the drug candidate and process concept.
Results from the Marine Fungi projects were presented at a dedicated scientific track at ELRIG - Research and Innovation Impact into Cancer
11. March 2014
The full program is available here: program
Johannes Imhoff, GEOMAR - Marine Fungi: Strategy and General Overview
Antje Labes, GEOMAR - Marine Fungi: Understanding the Biology of Marine Fungi for Produktion of Secondary Metabolites to Establish a Natural Produkt Library
Russell Cox, Leibniz University of Hannover - Understanding Fungal Biosynthetic Gene Clusters (available soon)
Phil Gribbon, European Screening Port: Marine Fungi - a Phenotypic Assay Approach to Identifying Anti-cancer Compounds
Eriko Takano, University of Manchester Biotechnology 2.0: Use of Synthetic Biology for Natural Products (available soon)
Isabel Coma, GlaxoSmithKline: Mining Natural Products Screening Data for Target Class Chemical Motifs (available soon)
Esther Schmitt, Novartis Pharma AG: Innovation and Tradition in Industrial Natural Products Research
Lutz Müller-Kuhrt, Analyticon Discovery Novel Strategies for Natural Product Based Macrocyclic Libraries (available soon)
Rebecca Goss, University of St. Andrews: Elucidating and Exploiting Biosynthesis (available soon)
Stephen Wrigley, Hypha Discovery Ltd: Marine Fungi - Charting the Chemistry of Hits from an Anticancer Screening Campaign
A. Tamminen/ M. Wiebe: Scopularide A production from the Marine Fungus Scopulariopsis brevicaulis
J. Silber et al.: Bioactive metabolites of a marine Calcarisporium sp.
K.S. Pedersen et al. : Phosphorylation dynamics in response to a novel anticancer compound from marine fungi
J. Landskron & K. Tjasken: Natural Products from Marine Fungi for the treatment of cancer
A. Stokka et al.: An EU-OPENSCREEN partner: The Chemical Biology Platform in Oslo